Your browser doesn't support javascript.
Show: 20 | 50 | 100
Results 1 - 1 de 1
Filter
Add filters
Database
Language
Document Type
Year range
1.
Antihistamine and cationic amphiphilic drugs, old molecules as new tools against the COVID-19?
Gitahy Falcao Faria, Clara; Weiner, Luisa; Petrignet, Julien; Hingray, Coraline; Ruiz De Pellon Santamaria, Ángel; Villoutreix, Bruno O; Beaune, Philippe; Leboyer, Marion; Javelot, Hervé.
Med Hypotheses ; 148: 110508, 2021 Mar.
Article in English | MEDLINE | ID: covidwho-1046208

ABSTRACT

Several studies have reported that certain psychoactive drugs could have a protective effect against SARS-CoV-2. Herein, we propose that antihistamines (anti-H1) and cationic amphiphilic drugs (CAD), specifically, have the capacity to disrupt virus entry and replication. In addition, several of these molecules have limited side effects and as such could be promising prophylactic candidates against SARS-CoV-2 infection.


Subject(s)
COVID-19 Drug Treatment , Histamine H1 Antagonists/pharmacology , SARS-CoV-2 , Surface-Active Agents/pharmacology , COVID-19/virology , Drug Repositioning , Humans , Models, Biological , Pandemics , SARS-CoV-2/drug effects , SARS-CoV-2/physiology , Virus Internalization/drug effects , Virus Replication/drug effects
SEND TO:
Email
Export
Print
RSS
XML
SELECTION OF CITATIONS
SEARCH DETAIL